Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 6/20 | 0.33 |
| ▸ | CES1 | P23141 | 6/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30757517 | 0.86 | — | — | |
| SCHEMBL6074622 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL11032946 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| SCHEMBL8795227 | 0.77 | MEN1 (0.44) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL856486 | 0.76 | — | — | |
| SCHEMBL9680510 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL19283724 | 0.76 | LMNA (0.54) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL5399043 | 0.76 | MEN1 (0.48) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL10496017 | 0.76 | MEN1 (0.43) | ALDH1A1KMT2AMEN1LMNABLM | |
| SCHEMBL15688292 | 0.75 | TSHR (0.41) | ALDH1A1KMT2AMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168940-B1 | 6,8,10-UNDECATRIEN-(3 OR 4)-ONE AND PERFUME COMPOSITION | HASEGAWA T CO LTD (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7795474-B2 | 6,8,10-undecatrien-3-one or 6,8,10-undecatrien-4-one, and aroma compositions | T. HASEGAWA CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-2168940-A9 | 6,8,10-UNDECATRIEN-(3 OR 4)-ONE AND PERFUME COMPOSITION | T. Hasegawa Co., Ltd. (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-20100137648-A1 | 6,8,10-UNDECATRIEN-3-ONE OR 6,8,10-UNDECATRIEN-4-ONE, AND AROMA COMPOSITIONS | T. HASEGAWA CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2168940-A1 | 6,8,10-UNDECATRIEN-(3 OR 4)-ONE AND PERFUME COMPOSITION | T. Hasegawa Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |
| EP-1585720-A1 | PROCESS FOR CONVERTING A CIS-TRANS MIXTURE OF SUBSTITUTED BENZYLIDENE AMINES INTO THE PURE CIS ISOMER | Pfizer Products Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1272484-B1 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | PFIZER PROD INC (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6878848-B2 | Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer | PFIZER INC (US) | 2005-04-12 | — | — | US | disclosed |
| US-20040254380-A1 | Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer | PFIZER INC | 2004-12-16 | — | — | US | disclosed |
| WO-2004043908-A1 | PROCESS FOR CONVERTING A CIS-TRANS MIXTURE OF SUBSTITUTED BENZYLIDENE AMINES INTO THE PURE CIS ISOMER | PFIZER PRODUCTS INC. (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC. | 2003-05-08 | — | — | US | disclosed |
| EP-1272484-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001077100-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2001-10-18 | — | — | WO | disclosed |
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254380-A1 | Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer | BDKRB1, BDKRB2, TACR1 | ALDH1A1 448/4885KMT2A 1249/4885MEN1 997/4885 |
| US-20100137648-A1 | 6,8,10-UNDECATRIEN-3-ONE OR 6,8,10-UNDECATRIEN-4-ONE, AND AROMA COMPOSITIONS | OR10J3, ALOX5, TAS2R13 | ALDH1A1 757/4885KMT2A 2871/4885MEN1 1355/4885 |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | TACR1, VIPR1, VIPR2 | ALDH1A1 732/4885KMT2A 1034/4885MEN1 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.