Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831095 | 0.88 | ALOX15 (0.53) | ALOX15 | |
| SCHEMBL8540507 | 0.86 | KDM4E (0.60) | ALOX15MAPT | |
| SCHEMBL29777 | 0.82 | MAPT (0.48) | MAPT | |
| SCHEMBL15622226 | 0.82 | HTR6 (0.50) | ALOX15MAPT | |
| SCHEMBL4126314 | 0.82 | ALDH1A1 (0.58) | MAPT | |
| SCHEMBL31486199 | 0.81 | ALOX5 (0.46) | ALOX15MAPT | |
| SCHEMBL15622314 | 0.81 | HTR6 (0.49) | ALOX15MAPT | |
| SCHEMBL31423315 | 0.81 | ALDH1A1 (0.46) | MAPT | |
| SCHEMBL8793660 | 0.80 | ALOX15 (0.85) | ALOX15 | |
| SCHEMBL8795754 | 0.80 | ALOX15 (0.61) | ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652239-A | TREATMENT OF STROKES, ISCHEMIC ATTACK, ANTAGONISTS OF EXCITATORY AMINO ACIDS GLUTAMATE AND ASPARTATE | IMPERIAL CHEMICAL COMPANY (GB) | 1997-07-29 | — | — | US | disclosed |
| EP-0512817-B1 | Pyridazinedione derivatives, their preparation and pharmaceutical applications | ZENECA LTD (GB) | 1997-02-19 | — | — | EP | disclosed |
| EP-0512817-A1 | Pyridazinedione derivatives, their preparation and pharmaceutical applications | ZENECA LIMITED (GB) | 1992-11-11 | — | — | EP | disclosed |