Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312376 | 0.85 | PTGS2 (0.38) | ABCC9ABCB1KDM4EKCNE1KCNQ1 | |
| SCHEMBL8316738 | 0.84 | ABCC9 (0.32) | ABCC9 | |
| SCHEMBL10381365 | 0.83 | ABCC9 (0.41) | ABCC9ABCB1KDM4E | |
| SCHEMBL8312895 | 0.82 | GABRA1 (0.37) | ABCC9KCNE1KCNQ1 | |
| SCHEMBL8795746 | 0.81 | ABCC9 (0.39) | ABCC9ABCB1KDM4EPTGER4KCNE1 | |
| SCHEMBL8313588 | 0.79 | OPRD1 (0.40) | — | |
| SCHEMBL8316122 | 0.78 | EPHX2 (0.30) | — | |
| SCHEMBL8794643 | 0.73 | ABCC9 (0.39) | ABCC9ABCB1KDM4EKCNE1KCNQ1 | |
| SCHEMBL8313718 | 0.71 | — | — | |
| SCHEMBL8313695 | 0.71 | KDM4E (0.34) | KDM4ECDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |