Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APEH | P13798 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519164 | 0.83 | NR4A2 (0.43) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL17900455 | 0.82 | PPME1 (0.49) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL27662268 | 0.82 | PPME1 (0.49) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL8797471 | 0.79 | PPME1 (0.42) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL1365701 | 0.79 | PKM (0.51) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL5269124 | 0.77 | MEN1 (0.42) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL8797951 | 0.76 | HTR6 (0.43) | PTPN1GSK3BHTR6LMNAMEN1 | |
| SCHEMBL17574711 | 0.75 | MEN1 (0.55) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL26054592 | 0.75 | PPME1 (0.46) | PPME1HTR6LMNAMEN1ALDH1A1 | |
| SCHEMBL9788986 | 0.75 | KLKB1 (0.48) | PTPN1GSK3BHTR6LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597291-B1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5321041-A | Antiallergens, antiinflammatory and anticaogulants | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0597291-A1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |