Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 2/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798410 | 0.87 | LRRK2 (0.34) | CYP11B2CYP11B1CYP19A1FLT3ABCC9 | |
| SCHEMBL8196440 | 0.84 | CYP11B2 (0.46) | CYP11B2CYP11B1CYP17A1CYP19A1CHRNB2 | |
| SCHEMBL9086171 | 0.82 | KCNH2 (0.42) | CYP11B2CYP11B1CYP17A1CYP19A1BACE1 | |
| SCHEMBL8797518 | 0.80 | METAP2 (0.35) | SQORKCNH2 | |
| SCHEMBL8796991 | 0.80 | POLB (0.40) | CYP11B2CYP11B1SCN9ANPY5RKCNH2 | |
| SCHEMBL8311321 | 0.80 | CYP11B2 (0.44) | CYP11B2CYP11B1CYP17A1CYP19A1CHRNB2 | |
| SCHEMBL9478589 | 0.73 | CYP11B2 (0.46) | CYP11B2CYP11B1CYP17A1CYP19A1SOAT2 | |
| SCHEMBL8196362 | 0.72 | CYP11B2 (0.48) | CYP11B2CYP11B1CYP17A1CYP19A1CHRNB2 | |
| SCHEMBL8797308 | 0.70 | FFAR1 (0.35) | ABCC9KCNH2 | |
| SCHEMBL9088354 | 0.69 | ABCC9 (0.38) | CYP11B2CYP11B1CYP19A1FLT3ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514942-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1997-03-05 | — | — | EP | disclosed |
| US-5493029-A | USEFUL IN TREATING ASTHMA AND HYPERTENSION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-02-20 | — | — | US | disclosed |
| US-5300511-A | Spiro-benzopyran derivatives and useful for treating asthma and hypertension | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-04-05 | — | — | US | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |