Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770579 | 0.74 | CYP2A6 (0.36) | DRD1 | |
| SCHEMBL20478484 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL20478847 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL4474329 | 0.61 | MAOA (0.33) | — | |
| SCHEMBL927218 | 0.60 | NOS3 (0.53) | — | |
| SCHEMBL19153122 | 0.60 | MAOA (0.41) | DRD1 | |
| SCHEMBL8271685 | 0.60 | DRD1 (0.39) | DRD1 | |
| SCHEMBL31310128 | 0.59 | APLNR (0.34) | — | |
| SCHEMBL20478625 | 0.59 | RORC (0.34) | — | |
| SCHEMBL6431761 | 0.58 | BRD4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758333-A1 | INTERMEDIATES IN PHARMACEUTICAL CAMPTOTHECIN PREPARATION | GLAXO WELLCOME INC. (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029917-A2 | INTERMEDIATES IN PHARMACEUTICAL CAMPTOTHECIN PREPARATION | GLAXO WELLCOME INC. (US) | 1995-11-09 | — | — | WO | disclosed |