Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799224 | 0.80 | AHR (0.33) | AHRCYP1B1MEN1KMT2ACRHBP | |
| SCHEMBL8799727 | 0.78 | AKR1C3 (0.33) | AHRCYP1B1MEN1KMT2ACRHBP | |
| SCHEMBL8797802 | 0.77 | SLC6A3 (0.32) | MEN1KMT2ACRHBPMC4RCRHR2 | |
| SCHEMBL7510534 | 0.75 | NOTUM (0.35) | MEN1KMT2ACRHBPMC4RCRHR2 | |
| SCHEMBL8994492 | 0.69 | MAPK14 (0.46) | AHRCYP1B1HSD11B1MEN1KMT2A | |
| SCHEMBL9191382 | 0.65 | AR (0.38) | AHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8799220 | 0.65 | AHR (0.38) | AHRCYP1B1MEN1KMT2AAKR1C3 | |
| SCHEMBL8799050 | 0.63 | KDM4E (0.32) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL7548622 | 0.62 | KDM4E (0.39) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9316592 | 0.62 | PTGS1 (0.37) | AHRCYP1B1MEN1KMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |