Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799397 | 0.78 | AHR (0.36) | AKR1C3AKR1C2AHRMEN1CRHBP | |
| SCHEMBL8797802 | 0.73 | SLC6A3 (0.32) | AKR1C3AKR1C2MEN1CRHBPMC4R | |
| SCHEMBL8799224 | 0.73 | AHR (0.33) | AKR1C3AKR1C2AHRMEN1CRHBP | |
| SCHEMBL7510534 | 0.68 | NOTUM (0.35) | AKR1C3AKR1C2MEN1CRHBPMC4R | |
| SCHEMBL5819704 | 0.61 | CTSS (0.33) | MEN1KMT2ASLC6A3 | |
| SCHEMBL8799220 | 0.59 | AHR (0.38) | AKR1C3AKR1C2AHRMEN1KMT2A | |
| SCHEMBL8799002 | 0.59 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL8799050 | 0.57 | KDM4E (0.32) | MEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL28561886 | 0.57 | PTGER1 (0.32) | — | |
| SCHEMBL9316592 | 0.57 | PTGS1 (0.37) | AKR1C3AKR1C2AHRMEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |