Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799777 | 0.91 | GPR35 (0.45) | GPR35RAB9AGHSRMEN1KMT2A | |
| SCHEMBL8800035 | 0.90 | GHSR (0.40) | RAB9AGHSRMEN1KMT2ATHRB | |
| SCHEMBL8800451 | 0.85 | TYK2 (0.42) | GHSRMEN1KMT2ATYK2 | |
| SCHEMBL8801121 | 0.83 | GPR35 (0.39) | GPR35RAB9AGHSRMEN1KMT2A | |
| SCHEMBL8799666 | 0.83 | GHSR (0.42) | GHSRMEN1KMT2APOLBPTGS2 | |
| SCHEMBL8799385 | 0.82 | GHSR (0.38) | RAB9AGHSRTHRBNPC1 | |
| SCHEMBL7816603 | 0.82 | MEN1 (0.38) | RAB9AGHSRMEN1KMT2ATHRB | |
| SCHEMBL7817213 | 0.81 | MEN1 (0.39) | GPR35RAB9AGHSRMEN1KMT2A | |
| SCHEMBL7816579 | 0.81 | GAA (0.46) | GPR35RAB9AMEN1KMT2APOLB | |
| SCHEMBL7825606 | 0.80 | GPR35 (0.43) | GPR35RAB9AGHSRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |