Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800035 | 0.92 | GHSR (0.40) | GHSRITGB1ITGA4ITGB7THRB | |
| SCHEMBL8800451 | 0.87 | TYK2 (0.42) | GHSRITGB1ITGA4ITGB7ALDH1A1 | |
| SCHEMBL8801121 | 0.85 | GPR35 (0.39) | GHSRTHRBRAB9AALDH1A1 | |
| SCHEMBL8799666 | 0.84 | GHSR (0.42) | GHSRALDH1A1 | |
| SCHEMBL7816603 | 0.83 | MEN1 (0.38) | GHSRITGB1ITGA4THRBRAB9A | |
| SCHEMBL7817213 | 0.83 | MEN1 (0.39) | GHSRITGB1ITGA4ITGB7TP53 | |
| SCHEMBL8799508 | 0.82 | GPR35 (0.41) | GHSRTHRBRAB9ANPC1 | |
| SCHEMBL8800075 | 0.80 | ITGB1 (0.39) | ITGB1ITGA4ALDH1A1 | |
| SCHEMBL8799550 | 0.80 | ALDH1A1 (0.38) | TP53RAB9AALDH1A1NPC1 | |
| SCHEMBL8798653 | 0.80 | PTGS2 (0.40) | GHSRTHRBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |