Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799411 | 0.88 | CYP4A11 (0.61) | CYP4F2CYP4A11SLC7A5MAPTFAAH | |
| SCHEMBL8799468 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2DHODHSLC16A3 | |
| SCHEMBL9118208 | 0.82 | PTGS2 (0.33) | CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL8800173 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11HPGD | |
| SCHEMBL8800010 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11HPGD | |
| SCHEMBL8466647 | 0.81 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1HPGD | |
| SCHEMBL9118405 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11HPGD | |
| SCHEMBL8802031 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11HPGD | |
| SCHEMBL8799349 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11HPGD | |
| SCHEMBL8799647 | 0.81 | CYP4F2 (0.44) | CYP4F2CYP4A11SLC7A5MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |