Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096982 | 0.83 | TSHR (0.37) | TSHRHSD11B1EPHX2GLAESR1 | |
| SCHEMBL2749102 | 0.78 | TSHR (0.59) | TSHREPHX2GLAESR1 | |
| SCHEMBL8096733 | 0.75 | LMNA (0.42) | HSD11B1NPSR1EPHX2 | |
| SCHEMBL1397649 | 0.72 | NPSR1 (0.46) | TSHRHSD11B1NPSR1EPHX2NAAA | |
| SCHEMBL2090342 | 0.70 | TSHR (0.37) | TSHRESR1 | |
| SCHEMBL2986988 | 0.69 | HSD11B1 (0.33) | TSHRHSD11B1NPSR1 | |
| SCHEMBL8098634 | 0.67 | TSHR (0.38) | TSHRESR1 | |
| SCHEMBL727714 | 0.66 | NPSR1 (0.48) | TSHRHSD11B1NPSR1GLA | |
| Acrylic Acid SCHEMBL27997933 | 0.66 | THRB (0.41) | TSHRHSD11B1NPSR1EPHX2GLA | |
| SCHEMBL16728244 | 0.62 | CHRNB2 (0.38) | TSHRHSD11B1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650406-A | ANTISCHIZOPHRENIC AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0757040-A1 | ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-02-05 | — | — | EP | disclosed |