Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353274 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL8801407 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL8800486 | 0.78 | CES2 (0.49) | ALDH1A1KDM4ELMNAGAACES2 | |
| SCHEMBL8799603 | 0.78 | FABP3 (0.49) | ALDH1A1KDM4ELMNATSHRCES2 | |
| SCHEMBL8800972 | 0.77 | FABP4 (0.52) | ALDH1A1LMNAGAATP53CES2 | |
| SCHEMBL8802097 | 0.75 | RAB9A (0.49) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL28285937 | 0.72 | MAPT (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL2362426 | 0.72 | LMNA (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL665133 | 0.72 | LMNA (0.55) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL5597507 | 0.71 | LMNA (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |