Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283136 | 0.77 | TRPA1 (0.44) | HPGDTSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL8801566 | 0.73 | SLC6A2 (0.48) | HPGDTSHRSLC6A2TAAR1SLC6A4 | |
| SCHEMBL8801211 | 0.73 | TRPA1 (0.46) | HPGDTSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL10693656 | 0.72 | ALOX5 (0.41) | HPGDTSHRLMNAL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL8800673 | 0.72 | SLC6A2 (0.47) | HPGDTSHRSLC6A2TAAR1SLC6A4 | |
| SCHEMBL8800678 | 0.71 | TSHR (0.42) | HPGDTSHRLMNAMEN1KMT2A | |
| SCHEMBL8801053 | 0.70 | TDP1 (0.38) | HPGDTSHRLMNAL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL22372374 | 0.70 | CTSD (0.36) | HPGDTSHRCTSLMEN1KMT2A | |
| SCHEMBL21056125 | 0.70 | SLC6A2 (0.48) | HPGDTSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL27515553 | 0.70 | SLC6A2 (0.48) | HPGDTSHRMEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |