Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277961 | 0.74 | GPR84 (0.41) | HSD11B1PLK1PLK3FAAHGPR84 | |
| SCHEMBL8802342 | 0.71 | — | — | |
| SCHEMBL8807946 | 0.69 | PTGS2 (0.35) | HSD11B1GPR84 | |
| SCHEMBL9267234 | 0.68 | S1PR1 (0.37) | HSD11B1PLK1PLK3FAAH | |
| SCHEMBL18374839 | 0.66 | TYR (0.44) | FAAH | |
| SCHEMBL22864099 | 0.66 | LIPG (0.42) | HSD11B1PLK1PLK3 | |
| SCHEMBL9287050 | 0.64 | GPR84 (0.34) | GPR84 | |
| SCHEMBL18374703 | 0.64 | TYR (0.47) | FAAH | |
| SCHEMBL20734526 | 0.64 | HSD11B1 (0.34) | HSD11B1PLK1PLK3FAAHGPR84 | |
| SCHEMBL28234439 | 0.63 | GPR84 (0.37) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995004038-A1 | SUBSTITUTED 2-ARYL-TRIFLUOROMETHYLPYRROLES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-09 | — | — | WO | disclosed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |