Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 4/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585288 | 0.77 | ALDH1A1 (0.52) | PDE4AALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL8516383 | 0.69 | TSHR (0.52) | ALDH1A1KDM4EHPGDTYMSKMT2A | |
| SCHEMBL7603908 | 0.69 | L3MBTL1 (0.43) | ALDH1A1KDM4EHPGDRAB9ATYMS | |
| SCHEMBL3170196 | 0.69 | GAA (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL13226838 | 0.69 | DYRK1A (0.42) | DYRK1ACCNKCDK12 | |
| SCHEMBL9232485 | 0.68 | KMT2A (0.44) | ALDH1A1KDM4ERAB9ATYMSKMT2A | |
| SCHEMBL4687124 | 0.68 | BRD4 (0.40) | ALDH1A1KDM4EHPGDTYMSKMT2A | |
| SCHEMBL38666143 | 0.68 | PDE4D (0.50) | PDE4AALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL30500790 | 0.68 | PDE4A (0.51) | PDE4AKDM4ENPSR1 | |
| SCHEMBL9521880 | 0.67 | CCNC (0.58) | ALDH1A1KDM4ERAB9AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433854-B1 | 3-Aminopyrazolo heterocycles, their use for the determination of hydrogen peroxide, hydrogen peroxide forming systems, peroxidase, peroxidant active substances or electron rich aromatic compounds, corresponding determination process and agents | BOEHRINGER MANNHEIM GMBH (DE) | 1997-06-18 | — | — | EP | disclosed |
| EP-0433854-A2 | 3-Aminopyrazolo heterocycles, their use for the determination of hydrogen peroxide, hydrogen peroxide forming systems, peroxidase, peroxidant active substances or electron rich aromatic compounds, corresponding determination process and agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |