Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550571 | 0.73 | TRPV4 (0.37) | — | |
| SCHEMBL8798526 | 0.70 | BDKRB2 (0.56) | — | |
| SCHEMBL7812727 | 0.69 | CA1 (0.34) | POLB | |
| SCHEMBL2850012 | 0.68 | DAO (0.37) | POLB | |
| SCHEMBL28955078 | 0.67 | HSD11B1 (0.41) | POLB | |
| SCHEMBL8454454 | 0.66 | CA1 (0.35) | — | |
| SCHEMBL6942963 | 0.66 | TSHR (0.54) | POLB | |
| SCHEMBL7812236 | 0.66 | ALDH1A1 (0.38) | POLB | |
| SCHEMBL859436 | 0.64 | CYP3A4 (0.36) | POLB | |
| SCHEMBL6945181 | 0.63 | KMT2A (0.56) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797576-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |