Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798277 | 0.83 | NPC1 (0.41) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL7570572 | 0.75 | NAMPT (0.55) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL7505880 | 0.74 | SGMS2 (0.45) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL5234312 | 0.72 | RAB9A (0.44) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL7493834 | 0.71 | KMT2A (0.65) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL7578693 | 0.69 | L3MBTL1 (0.51) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL8573120 | 0.68 | ALOX5 (0.47) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL10345079 | 0.68 | ALOX5 (0.47) | KMT2AMEN1KDM4EKDM6BKDM4A | |
| SCHEMBL11433211 | 0.68 | ALOX5 (0.50) | KMT2AKDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL8797776 | 0.68 | KMT2A (0.52) | KMT2AL3MBTL1NPC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |