Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489174 | 0.82 | NR1H2 (0.40) | NR1H2NR1H3LCK | |
| SCHEMBL9836013 | 0.82 | LMNA (0.39) | PTGS2MEN1KMT2AGSK3BNR1H2 | |
| SCHEMBL6388610 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1NR1H2NR1H3 | |
| SCHEMBL12810280 | 0.79 | PTGS1 (0.45) | PTGS2MEN1KMT2AALDH1A1NR1H2 | |
| SCHEMBL13524782 | 0.79 | KMT2A (0.41) | PTGS2MEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL13760513 | 0.78 | LMNA (0.40) | PTGS2MEN1KMT2AALDH1A1NR1H2 | |
| SCHEMBL19304186 | 0.77 | PTGS2 (0.37) | PTGS2MEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL6693898 | 0.77 | PTGS2 (0.45) | PTGS2GSK3BNR1H2NR1H3 | |
| SCHEMBL21419681 | 0.77 | GSK3B (0.36) | PTGS2MEN1KMT2AGSK3B | |
| SCHEMBL13524788 | 0.77 | KMT2A (0.40) | PTGS2MEN1KMT2AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811625-A2 | Process for preparing diketopyrrolopyrrole derivatives | Ciba SC Holding AG (CH) | 1997-12-10 | — | — | EP | disclosed |