Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29550931 | 0.81 | TSHR (0.52) | ALDH1A1KDM4ETDP1MAPTCYP1A2 | |
| SCHEMBL422881 | 0.81 | TSHR (0.52) | ALDH1A1KDM4ETDP1MAPTCYP1A2 | |
| SCHEMBL492531 | 0.78 | CYP2C19 (0.51) | ALDH1A1L3MBTL1TDP1LMNACYP1A2 | |
| SCHEMBL5795930 | 0.78 | SLC6A12 (0.36) | ALDH1A1KDM4EL3MBTL1TSHRRAB9A | |
| SCHEMBL9144675 | 0.77 | SLC6A12 (0.37) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL29922180 | 0.77 | SLC6A12 (0.36) | ALDH1A1KDM4EL3MBTL1GAAMAPT | |
| SCHEMBL9686323 | 0.77 | KEAP1 (0.51) | ALDH1A1KDM4ETDP1LMNAMAPT | |
| SCHEMBL27446237 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1TDP1GAA | |
| SCHEMBL2082473 | 0.76 | PKM (0.43) | ALDH1A1KDM4ETDP1GAAMAPT | |
| SCHEMBL29980368 | 0.76 | PKM (0.43) | ALDH1A1KDM4ETDP1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996002540-A1 | HETEROCYCLYL-1-PHENYL SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| WO-1996002539-A1 | SUBSTITUTED TRIAZOLYL METHYL PHENYL NAPHTHYRIDONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| CN-1097423-A | Quinolone-and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-01-18 | — | — | CN | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |