Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800500 | 0.78 | MTNR1A (0.36) | MTNR1AMTNR1BTSHRCYP2C9CYP2C19 | |
| SCHEMBL9570187 | 0.78 | TSHR (0.43) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7277764 | 0.74 | MIF (0.53) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8309560 | 0.74 | TSHR (0.44) | MTNR1AMTNR1BTSHRALDH1A1NPC1 | |
| SCHEMBL27477104 | 0.72 | MME (0.50) | — | |
| SCHEMBL8800805 | 0.72 | PPARG (0.41) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5647796 | 0.72 | TRPA1 (0.43) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8801705 | 0.71 | PPARG (0.40) | TSHRALDH1A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL23766641 | 0.70 | PRMT5 (0.59) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL15890234 | 0.70 | HPGD (0.60) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |