Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410966 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL6054861 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL12511057 | 0.75 | ACHE (0.74) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL11267018 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL3202573 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ATSHRACHE | |
| SCHEMBL15652117 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL8801242 | 0.74 | CYP19A1 (0.50) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL11705310 | 0.74 | CYP11B1 (0.56) | ALDH1A1POLB | |
| SCHEMBL23780328 | 0.73 | NPC1 (0.47) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL301933 | 0.73 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ATSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |