Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827494 | 0.86 | PARP14 (0.37) | GHSRPARP14GPR35MEN1KMT2A | |
| SCHEMBL7831900 | 0.85 | MAPT (0.40) | GHSRPARP14GPR35MEN1KMT2A | |
| SCHEMBL8800035 | 0.84 | GHSR (0.40) | GHSRMEN1KMT2ATHRBMAPT | |
| SCHEMBL7828389 | 0.82 | PARP14 (0.35) | GHSRPARP14GPR35MEN1KMT2A | |
| SCHEMBL8800451 | 0.81 | TYK2 (0.42) | GHSRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8801121 | 0.80 | GPR35 (0.39) | GHSRGPR35MEN1KMT2ATHRB | |
| SCHEMBL8799666 | 0.79 | GHSR (0.42) | GHSRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8799385 | 0.79 | GHSR (0.38) | GHSRTHRB | |
| SCHEMBL7826683 | 0.78 | MAPT (0.43) | PARP14MEN1KMT2ATHRBMAPT | |
| SCHEMBL7816603 | 0.77 | MEN1 (0.38) | GHSRMEN1KMT2ATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |