Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801909 | 0.87 | SLC22A6 (0.48) | PARP14MPLPIM3PIM1KIF11 | |
| SCHEMBL8391232 | 0.79 | MAPT (0.48) | MPLMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8387263 | 0.73 | KIF11 (0.47) | PARP14MPLPIM3PIM1KIF11 | |
| SCHEMBL9056003 | 0.71 | SLC22A6 (0.51) | PARP14MPLPIM3PIM1KIF11 | |
| SCHEMBL8389286 | 0.71 | MAPT (0.48) | PARP14MPLPIM3PIM1KIF11 | |
| SCHEMBL9057701 | 0.70 | HTT (0.49) | KIF11MAPTMAPK1MEN1KMT2A | |
| SCHEMBL4786156 | 0.69 | SLC22A6 (0.55) | PARP14MPLPIM3PIM1KIF11 | |
| SCHEMBL8388289 | 0.68 | SLC22A6 (0.48) | KIF11MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8803144 | 0.68 | SLC22A6 (0.41) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL8802131 | 0.67 | SLC22A6 (0.40) | KIF11MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |