Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | SPR | P35270 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 8/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802984 | 0.98 | NOTUM (0.60) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL8802739 | 0.81 | NOTUM (0.65) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL8802296 | 0.80 | FAAH (0.63) | MTNR1AKDM4EMAPT | |
| SCHEMBL8802151 | 0.79 | TRPM8 (0.66) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL8194888 | 0.77 | NOTUM (0.70) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL20242784 | 0.77 | NOTUM (0.78) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL14077525 | 0.76 | NOTUM (0.72) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL4852117 | 0.76 | FAAH (0.74) | NOTUMMTNR1AMTNR1BSPRTRPV1 | |
| SCHEMBL4512654 | 0.76 | MTNR1A (1.00) | NOTUMMTNR1AMTNR1BSPRMPO | |
| SCHEMBL17437585 | 0.76 | MTNR1A (0.61) | NOTUMMTNR1AMTNR1BSPRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | claimed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | claimed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | claimed |
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5580878-A | TREATING SLEEP DISORDERS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |
| US-5403851-A | Central nervous system and psychological disorders | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-04-04 | — | — | US | disclosed |