Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801521 | 0.85 | KDM4E (0.51) | KDM4EGAAGLAMTNR1AMTNR1B | |
| SCHEMBL6768454 | 0.80 | MTNR1A (0.59) | KDM4EMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL8801813 | 0.80 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL8801366 | 0.74 | CA2 (0.52) | KDM4EGAAGLAMTNR1AMTNR1B | |
| SCHEMBL1180269 | 0.74 | KDM4E (0.61) | KDM4EGAAGLAMTNR1AMTNR1B | |
| SCHEMBL7426912 | 0.73 | MTNR1A (0.46) | KDM4EGAAMTNR1AMTNR1BMAPT | |
| SCHEMBL531085 | 0.71 | ELANE (0.61) | GAAMAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL17422716 | 0.71 | ALOX5 (0.46) | KDM4EMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL7055922 | 0.71 | TUBB1 (0.55) | KDM4EGAAMTNR1AMTNR1BMAPK1 | |
| SCHEMBL12986903 | 0.70 | KDM4E (1.00) | KDM4EGAAGLAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |