Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984140 | 0.87 | CA2 (0.50) | CA2PDGFRBPDGFRAFGFR1MTNR1A | |
| SCHEMBL8802023 | 0.75 | PPARG (0.49) | KMT2AMEN1KDM4EMAPTF2 | |
| SCHEMBL8802154 | 0.74 | KDM4E (0.53) | CA2PDGFRBPDGFRAFGFR1KMT2A | |
| SCHEMBL531085 | 0.73 | ELANE (0.61) | KMT2AGAANPC1RAB9AMAPT | |
| SCHEMBL8801521 | 0.73 | KDM4E (0.51) | CA2PDGFRBPDGFRAFGFR1KMT2A | |
| SCHEMBL5129029 | 0.72 | ITK (0.56) | F2ITK | |
| SCHEMBL3193871 | 0.71 | LOXL2 (0.60) | F2 | |
| SCHEMBL30105384 | 0.71 | LOXL2 (0.60) | F2 | |
| SCHEMBL9949523 | 0.71 | FLT3 (0.57) | PDGFRBPDGFRAKDM4EFLT3ALDH1A1 | |
| SCHEMBL8802592 | 0.71 | HDAC1 (0.45) | CA2KMT2AMEN1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |