Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805090 | 0.78 | CDK5 (0.41) | KDM4EALDH1A1HTTGAABLM | |
| SCHEMBL453483 | 0.77 | MAPK1 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL453482 | 0.77 | MAPK1 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL7744270 | 0.76 | MAPK1 (0.40) | KDM4EALDH1A1HTTGAABLM | |
| SCHEMBL7744286 | 0.75 | ALDH1A1 (0.39) | KDM4EALDH1A1HTTGAABLM | |
| SCHEMBL9243746 | 0.73 | ADORA1 (0.39) | KDM4EALDH1A1HTTGAABLM | |
| SCHEMBL29267975 | 0.73 | SLC29A1 (0.42) | KDM4EALDH1A1HTTMAPK1TDP1 | |
| SCHEMBL9241942 | 0.70 | P2RY2 (0.39) | KDM4EALDH1A1HTTMAPK1TDP1 | |
| SCHEMBL3989534 | 0.69 | SLC29A1 (0.44) | MAPK1HIF1ACYP1A2STAT6TP53 | |
| SCHEMBL9240204 | 0.69 | P2RY2 (0.40) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506892-B1 | BORONATED NUCLEOSIDES | BORON BIOLOG INC (US) | 1997-10-08 | — | — | EP | claimed |
| US-5130302-A | Antiinflammatory agents or antitumor agents | BORON BILOGICALS, INC. (US) | 1992-07-14 | — | — | US | claimed |
| EP-0506892-B1 | BORONATED NUCLEOSIDES | BORON BIOLOG INC (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0506892-A4 | BORONATED NUCLEOSIDES | — | 1993-03-31 | — | — | EP | disclosed |
| EP-0506892-A1 | BORONATED NUCLEOSIDES. | BORON BIOLOG INC (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5130302-A | Antiinflammatory agents or antitumor agents | BORON BILOGICALS, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| WO-1991009048-A1 | BORONATED NUCLEOSIDES | BARON BIOLOGICALS, INC. (US) | 1991-06-27 | — | — | WO | disclosed |