Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798099 | 0.86 | VCAM1 (0.34) | VCAM1LTA4HMTNR1AMTNR1BLPAR1 | |
| SCHEMBL8798236 | 0.86 | MEN1 (0.36) | CA1CA2MTNR1AMTNR1BPPARG | |
| SCHEMBL8797685 | 0.82 | HDAC1 (0.34) | VCAM1LTA4HLPAR1PPARGPPARD | |
| SCHEMBL8799426 | 0.82 | ACHE (0.42) | CA1CA2MTNR1AMTNR1BLPAR1 | |
| SCHEMBL8707922 | 0.74 | CA1 (0.41) | VCAM1CA1CA2LPAR1HDAC1 | |
| SCHEMBL281995 | 0.74 | NPC1 (0.39) | CA1CA2PPARGPPARDPPARA | |
| SCHEMBL8804341 | 0.73 | LMNA (0.34) | MTNR1AMTNR1BPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL6245752 | 0.73 | NPC1 (0.39) | CA1CA2PPARGPPARDPPARA | |
| SCHEMBL3740322 | 0.72 | RAB9A (0.38) | CA1CA2PPARGPPARDPPARA | |
| SCHEMBL8704676 | 0.71 | MAPK14 (0.53) | CA1CA2LPAR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |