Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804341 | 0.87 | LMNA (0.34) | MEN1KMT2AMTNR1AMTNR1BABCC1 | |
| SCHEMBL8799596 | 0.86 | VCAM1 (0.39) | MEN1KMT2ACA1CA2MTNR1A | |
| SCHEMBL8799426 | 0.80 | ACHE (0.42) | CA1CA2MTNR1AMTNR1BNPC1 | |
| SCHEMBL8797685 | 0.76 | HDAC1 (0.34) | MEN1KMT2ALMNAHDAC6HDAC1 | |
| SCHEMBL3740322 | 0.74 | RAB9A (0.38) | CA1CA2LMNANPC1MAPT | |
| SCHEMBL8798368 | 0.74 | SMN1; SMN2 (0.39) | KMT2AMTNR1AMTNR1BLMNANPC1 | |
| SCHEMBL8798099 | 0.73 | VCAM1 (0.34) | MEN1KMT2AMTNR1AMTNR1BLMNA | |
| SCHEMBL281995 | 0.72 | NPC1 (0.39) | MEN1KMT2ACA1CA2LMNA | |
| Hydrochloric Acid SCHEMBL6245752 | 0.71 | NPC1 (0.39) | MEN1KMT2ACA1CA2LMNA | |
| SCHEMBL8708827 | 0.69 | TSHR (0.56) | MEN1KMT2ACA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |