Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804354 | 1.00 | GAA (0.33) | GAAMAOBMAOAACHEKMT2A | |
| SCHEMBL8803662 | 0.81 | MAOB (0.37) | GAAMAOBMAOAACHEKMT2A | |
| SCHEMBL8803660 | 0.81 | MAOB (0.37) | GAAMAOBMAOAACHEKMT2A | |
| SCHEMBL8804151 | 0.76 | RAB9A (0.42) | GAAMAOBMAOAACHEKMT2A | |
| SCHEMBL8804204 | 0.70 | NPC1 (0.43) | — | |
| SCHEMBL8805340 | 0.68 | FAAH (0.48) | MAOBMAOAACHEKMT2AMEN1 | |
| SCHEMBL8802784 | 0.67 | MAOA (0.36) | MAOBMAOAACHE | |
| SCHEMBL8802800 | 0.67 | MAOA (0.36) | MAOBMAOAACHE | |
| SCHEMBL8802792 | 0.67 | MAOA (0.36) | MAOBMAOAACHE | |
| SCHEMBL8803219 | 0.67 | MAOB (0.63) | MAOBMAOAACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |