Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804212 | 0.85 | MAOB (0.53) | MAOBMAOAACHE | |
| SCHEMBL8806070 | 0.80 | ABCC1 (0.51) | RAB9APOLBATMGAAABCC1 | |
| SCHEMBL8804984 | 0.77 | GAA (0.38) | PPARGPPARDPPARARIPK1GAA | |
| SCHEMBL8804351 | 0.76 | GAA (0.33) | GAAKMT2AMAOBMAOAACHE | |
| SCHEMBL8804354 | 0.76 | GAA (0.33) | GAAKMT2AMAOBMAOAACHE | |
| SCHEMBL8803886 | 0.75 | TRPV1 (0.33) | RIPK1GAAKMT2A | |
| SCHEMBL8804204 | 0.74 | NPC1 (0.43) | RAB9APOLBNPC1 | |
| SCHEMBL8805340 | 0.71 | FAAH (0.48) | POLBKMT2AMAOBMAOAACHE | |
| SCHEMBL8803979 | 0.71 | SOAT2 (0.49) | RIPK1GAAKMT2AMEN1 | |
| SCHEMBL8804148 | 0.71 | MAOB (0.41) | RAB9AGAAABCC1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |