Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.48 |
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802623 | 0.80 | KDM4E (0.51) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL8802608 | 0.77 | CHRNB2 (0.57) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL7278288 | 0.74 | HTR3E (0.56) | CHRNA3HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL7271032 | 0.74 | HTR3E (0.56) | CHRNA3HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL27249759 | 0.72 | MEN1 (0.72) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL7502329 | 0.71 | HTR3A (0.70) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL27249716 | 0.70 | RBP4 (0.65) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL31575332 | 0.70 | SSTR4 (0.44) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL31302274 | 0.70 | KDM4E (0.66) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 | |
| SCHEMBL1563104 | 0.70 | KDM4E (0.66) | KDM4ECHRNA3HTR3AHTR3ESLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4266873-A | — | — | None | — | — | JP | disclosed |
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| JP-H04266873-A | PIPERIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO LTD | 1992-09-22 | — | — | JP | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |