Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL401463 | 0.75 | DRD2 (0.50) | LMNAMEN1KMT2ATDP1PARP1 | |
| SCHEMBL11001148 | 0.72 | LMNA (0.41) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL26370481 | 0.69 | HPGD (0.46) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5434419 | 0.66 | MCL1 (0.41) | LMNAKMT2APARP1HTR2AHTR2C | |
| SCHEMBL405139 | 0.66 | DRD2 (0.48) | ALDH1A1HSD17B10PARP1USP2HPGD | |
| SCHEMBL6837082 | 0.65 | MEN1 (0.41) | MEN1KMT2APARP1HTR2AHTR2C | |
| SCHEMBL406231 | 0.64 | DRD2 (0.47) | ALDH1A1HSD17B10PARP1USP2HPGD | |
| SCHEMBL27989542 | 0.64 | MTNR1A (0.40) | LMNAMEN1KMT2ATDP1PARP1 | |
| SCHEMBL25030544 | 0.63 | MEN1 (0.42) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL854184 | 0.63 | PARP1 (0.61) | LMNAMEN1KMT2AHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9143182-A | — | — | None | — | — | JP | disclosed |
| JP-H09143182-A | NEW 5-6-DIHYDROPYRROLO(3,2,1-IJ)QUINAZOLINE-1-ONE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1997-06-03 | — | — | JP | disclosed |