Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704258 | 0.78 | TSHR (0.48) | IDO1AGXTTSHRMAOAHTR2A | |
| SCHEMBL6239315 | 0.71 | TSHR (0.50) | IDO1TSHRSIGMAR1SMN1; SMN2 | |
| SCHEMBL25985295 | 0.69 | TSHR (0.47) | TSHRSIGMAR1SMN1; SMN2 | |
| SCHEMBL28530084 | 0.69 | SIGMAR1 (0.47) | IDO1TSHRMAOASIGMAR1HTR2A | |
| SCHEMBL167415 | 0.69 | MEN1 (0.73) | IDO1MAOASIGMAR1MC4RMC5R | |
| SCHEMBL10948517 | 0.68 | NPC1 (0.47) | IDO1AGXTTSHRMAOAHTR2A | |
| SCHEMBL1230769 | 0.68 | IDO1 (0.38) | IDO1AGXTTSHRMAOASIGMAR1 | |
| SCHEMBL10481808 | 0.67 | TSHR (0.48) | IDO1AGXTTSHRLTA4H | |
| SCHEMBL28895320 | 0.67 | TSHR (0.48) | IDO1AGXTTSHRMAOASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10382368 | 0.67 | MEN1 (0.70) | IDO1MAOASIGMAR1MC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543303-B1 | Hydrophilic hydrogels having a high swelling capacity | HOECHST AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| US-5331059-A | Absorbent materials, acrylic acid polymers crosslinked with diglycidyl phosphonates | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| EP-0543303-A1 | Hydrophilic hydrogels having a high swelling capacity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-26 | — | — | EP | disclosed |