Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801356 | 0.93 | LTB4R (0.40) | LTB4RLTB4R2PKM | |
| SCHEMBL8801516 | 0.87 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL8802594 | 0.81 | LTB4R (0.42) | LTB4RLTB4R2PKM | |
| SCHEMBL8801953 | 0.79 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL8801777 | 0.79 | LTB4R (0.56) | LTB4RLTB4R2 | |
| SCHEMBL8806843 | 0.78 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8805234 | 0.76 | TSPO (0.43) | LTB4RLTB4R2 | |
| SCHEMBL8802251 | 0.75 | GABRP (0.37) | LTB4RLTB4R2 | |
| SCHEMBL8802622 | 0.75 | GABRA1 (0.41) | — | |
| SCHEMBL8801587 | 0.74 | PLA2G2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |