Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809426 | 0.89 | KMT2A (0.51) | MEN1KMT2AMCHR1MAPTNPC1 | |
| SCHEMBL8806857 | 0.86 | MEN1 (0.48) | MEN1KMT2AMCHR1MAPTLMNA | |
| SCHEMBL8807455 | 0.79 | MEN1 (0.53) | MEN1KMT2AMCHR1MAPTLMNA | |
| SCHEMBL8807451 | 0.77 | ACHE (0.55) | MEN1KMT2AMCHR1CYP3A4 | |
| SCHEMBL8807078 | 0.77 | MAPT (0.46) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL8808377 | 0.77 | MAPT (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8810137 | 0.74 | MAPT (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8815541 | 0.74 | MAOB (0.46) | MCHR1MAPTLMNANPC1RAB9A | |
| SCHEMBL8807114 | 0.74 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL8809008 | 0.74 | MAPT (0.39) | MEN1KMT2AMCHR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |