Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858149 | 0.84 | OPRK1 (0.38) | ALDH1A1RIPK1MEN1KMT2A | |
| SCHEMBL8659654 | 0.79 | RIPK1 (0.36) | ALDH1A1KDM4ERIPK1RORCOPRM1 | |
| SCHEMBL8661413 | 0.78 | UTS2R (0.38) | ALDH1A1HTR2BMEN1KMT2A | |
| SCHEMBL8660376 | 0.77 | RIPK1 (0.37) | RIPK1MEN1MAPTKMT2A | |
| SCHEMBL8661071 | 0.76 | MAPT (0.38) | ALDH1A1RIPK1MEN1MAPTKMT2A | |
| SCHEMBL8660036 | 0.76 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL8662488 | 0.76 | MTNR1B (0.38) | RIPK1MEN1KMT2A | |
| SCHEMBL8809230 | 0.76 | PIK3CD (0.34) | RIPK1 | |
| SCHEMBL8662712 | 0.75 | RIPK1 (0.38) | RIPK1OPRM1MEN1KMT2A | |
| SCHEMBL8662095 | 0.75 | PIK3CD (0.40) | RIPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739335-A4 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS INC (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0739335-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018792-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |