Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
| ▸ | ESRRA | P11474 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.30 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811090 | 0.89 | KDM1A (0.38) | KDM1AC5AR1EPHX2PPARG | |
| SCHEMBL8811868 | 0.88 | PARP1 (0.40) | DAOPARP1PTGDR2KDM1A | |
| SCHEMBL8809597 | 0.87 | PARP1 (0.47) | PARP1 | |
| SCHEMBL8813445 | 0.87 | HTR6 (0.40) | PARP1 | |
| SCHEMBL8810643 | 0.86 | TACR1 (0.39) | PARP1 | |
| SCHEMBL8808968 | 0.81 | PPARG (0.41) | DAOPARP1PTGDR2KDM1AC5AR1 | |
| SCHEMBL8810446 | 0.81 | PPARG (0.38) | PPARG | |
| SCHEMBL8809697 | 0.80 | HTR6 (0.42) | — | |
| SCHEMBL8812495 | 0.79 | TNF (0.39) | — | |
| SCHEMBL8808816 | 0.79 | HTR6 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |