Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809597 | 0.93 | PARP1 (0.47) | TACR1PARP1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8813445 | 0.91 | HTR6 (0.40) | PARP1KDM4ESMN1; SMN2MAPTADCYAP1R1 | |
| SCHEMBL8809453 | 0.87 | MPO (0.38) | PARP1SMN1; SMN2LMNA | |
| SCHEMBL8808975 | 0.86 | DAO (0.34) | PARP1 | |
| SCHEMBL8685833 | 0.84 | HTR6 (0.43) | LMNA | |
| SCHEMBL8810664 | 0.84 | MPO (0.46) | KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL8811090 | 0.84 | KDM1A (0.38) | — | |
| SCHEMBL8810754 | 0.84 | PARP1 (0.41) | PARP1KDM4EHTTSMN1; SMN2MAPT | |
| SCHEMBL8810937 | 0.83 | TNF (0.40) | PARP1 | |
| SCHEMBL8812580 | 0.83 | TNF (0.37) | PARP1KDM4EHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |