Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 9/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808975 | 0.89 | DAO (0.34) | KDM1AEPHX2C5AR1PPARG | |
| SCHEMBL8808936 | 0.89 | KDM1A (0.44) | KDM1ATDP1C5AR1CHRM1ALDH1A1 | |
| SCHEMBL8809697 | 0.86 | HTR6 (0.42) | ALDH1A1 | |
| SCHEMBL8813445 | 0.85 | HTR6 (0.40) | ALDH1A1 | |
| SCHEMBL8813825 | 0.84 | CYP19A1 (0.39) | ALDH1A1 | |
| SCHEMBL8810643 | 0.84 | TACR1 (0.39) | — | |
| SCHEMBL8685833 | 0.84 | HTR6 (0.43) | ALDH1A1 | |
| SCHEMBL8812495 | 0.83 | TNF (0.39) | ALDH1A1 | |
| SCHEMBL8809597 | 0.83 | PARP1 (0.47) | ALDH1A1MKNK1MKNK2 | |
| SCHEMBL8809200 | 0.82 | PDE4A (0.33) | ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |