Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850964 | 0.79 | MEN1 (0.48) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL3160320 | 0.76 | MAPK14 (0.42) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL15741508 | 0.76 | NPC1 (0.43) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL13363877 | 0.76 | ERBB2 (0.39) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3755589 | 0.76 | IKBKB (0.41) | HSD17B10KDM4ELMNAHPGD | |
| SCHEMBL8810056 | 0.75 | BRD4 (0.44) | CYP2A6BRD4ALDH1A1DRD1ALDH1A3 | |
| SCHEMBL2449809 | 0.75 | ALOX15 (0.48) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL5280816 | 0.75 | PDE3B (0.57) | CYP2A6BRD4ALDH1A1PDE3BPDE3A | |
| SCHEMBL5223142 | 0.74 | MEN1 (0.53) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8507165 | 0.74 | MAP2K4 (0.50) | ALDH1A1HSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |