Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808702 | 0.86 | AGER (0.53) | MEN1KMT2AAGERMTNR1AG6PC1 | |
| SCHEMBL9056397 | 0.83 | G6PC1 (0.41) | MEN1KMT2AAGERMTNR1AG6PC1 | |
| SCHEMBL8811704 | 0.77 | AGER (0.44) | AGERMTNR1AG6PC1PPARGPPARA | |
| SCHEMBL8635902 | 0.73 | LTA4H (0.46) | MEN1KMT2ALTA4H | |
| SCHEMBL8639309 | 0.71 | LTA4H (0.47) | MEN1KMT2ALTA4H | |
| SCHEMBL27323330 | 0.71 | SLC18A3 (0.45) | AGERMTNR1AG6PC1 | |
| SCHEMBL28856725 | 0.70 | G6PC1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9232768 | 0.69 | NPY5R (0.40) | MTOR | |
| SCHEMBL16839457 | 0.68 | TEAD1 (0.51) | MEN1KMT2ALTA4H | |
| SCHEMBL8071958 | 0.68 | MAPK1 (0.48) | MEN1KMT2AAGERMTNR1AG6PC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |