Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808702 | 0.86 | AGER (0.53) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL8809140 | 0.83 | PSEN1 (0.42) | G6PC1AGERMTNR1AMEN1KMT2A | |
| SCHEMBL8811704 | 0.77 | AGER (0.44) | G6PC1AGERMTNR1A | |
| SCHEMBL8635902 | 0.75 | LTA4H (0.46) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8806703 | 0.75 | G6PC1 (0.48) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL8639309 | 0.74 | LTA4H (0.47) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL27323330 | 0.73 | SLC18A3 (0.45) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL9232768 | 0.71 | NPY5R (0.40) | HRH3KCNH2 | |
| SCHEMBL28354860 | 0.70 | G6PC1 (0.51) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL8071958 | 0.70 | MAPK1 (0.48) | G6PC1AGERMTNR1AUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |