Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810209 | 0.90 | CYP19A1 (0.40) | CYP19A1APP | |
| SCHEMBL8809489 | 0.89 | ALDH1A1 (0.41) | L3MBTL1PIK3R1PIK3CACHRM3CYP19A1 | |
| SCHEMBL8685833 | 0.86 | HTR6 (0.43) | CYP19A1APPHTR6MPO | |
| SCHEMBL8810664 | 0.85 | MPO (0.46) | CYP19A1HTR6MPO | |
| SCHEMBL8811872 | 0.85 | SLC2A1 (0.41) | CYP11B1CYP11B2HTR6 | |
| SCHEMBL8809719 | 0.83 | SLC2A1 (0.43) | L3MBTL1PIK3R1PIK3CAROCK2MPO | |
| SCHEMBL8809597 | 0.83 | PARP1 (0.47) | CHRM3 | |
| SCHEMBL8812025 | 0.82 | F10 (0.40) | MPO | |
| SCHEMBL8810937 | 0.82 | TNF (0.40) | HTR6MPO | |
| SCHEMBL8809453 | 0.82 | MPO (0.38) | CYP19A1HTR6MPOBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |