Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593281 | 0.93 | PLA2G7 (0.34) | MEN1KMT2ALMNACASP6ASAH1 | |
| SCHEMBL8595503 | 0.82 | POLB (0.39) | POLBLMNAASAH1ALDH1A1 | |
| SCHEMBL8518008 | 0.81 | MEN1 (0.34) | POLBMEN1KMT2ALMNA | |
| SCHEMBL27494322 | 0.81 | LMNA (0.39) | MAPTPOLBMEN1KMT2ALMNA | |
| SCHEMBL8591251 | 0.81 | HRH3 (0.39) | HRH3TP53MAPTPOLBMEN1 | |
| SCHEMBL20971523 | 0.79 | PLAAT3 (0.47) | HRH3TP53MAPTPOLBLMNA | |
| SCHEMBL20971533 | 0.79 | PLAAT3 (0.47) | HRH3TP53MAPTPOLBLMNA | |
| SCHEMBL8522255 | 0.79 | PLAAT3 (0.47) | HRH3TP53MAPTPOLBLMNA | |
| SCHEMBL8438262 | 0.79 | PLAAT3 (0.47) | HRH3TP53MAPTPOLBLMNA | |
| SCHEMBL8442091 | 0.79 | PLAAT3 (0.47) | HRH3TP53MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |