Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | GLP1R | P43220 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467268 | 0.77 | GLP1R (0.34) | GLP1R | |
| SCHEMBL7472397 | 0.77 | GRIN1 (0.35) | MTNR1AMTNR1BGLP1RRAB9A | |
| SCHEMBL7470559 | 0.76 | HRH4 (0.32) | GLP1R | |
| SCHEMBL7676315 | 0.72 | ALDH1A1 (0.40) | NPC1RAB9A | |
| SCHEMBL7468298 | 0.70 | KMT2A (0.37) | NPC1RAB9A | |
| SCHEMBL8784365 | 0.69 | HRH4 (0.34) | — | |
| SCHEMBL7466499 | 0.69 | HRH4 (0.35) | — | |
| SCHEMBL8784394 | 0.69 | HRH4 (0.35) | — | |
| SCHEMBL7462801 | 0.68 | CCR4 (0.36) | GLP1R | |
| SCHEMBL7676275 | 0.68 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Pfizer Limited (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |