Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406198 | 0.92 | RXRA (0.49) | PARP15PARP10PARP14MAOBRXRA | |
| SCHEMBL8167295 | 0.89 | PTGER1 (0.46) | RXRAPTGER1ALDH1A1LMNARAB9A | |
| SCHEMBL27430980 | 0.81 | PDCD1 (0.41) | MAOBPTGER1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8162467 | 0.81 | RXRA (0.55) | RXRAPTGER1MEN1ALDH1A1KMT2A | |
| SCHEMBL1907786 | 0.81 | RXRA (0.53) | RXRAPTGER1ALDH1A1LMNARAB9A | |
| SCHEMBL7662467 | 0.79 | CCR5 (0.45) | RXRAPTGER1ALDH1A1LMNARAB9A | |
| SCHEMBL8161455 | 0.78 | PTGER1 (0.54) | RXRAPTGER1MRGPRX4 | |
| SCHEMBL7816483 | 0.77 | GBA1 (0.46) | PARP1MEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL8162566 | 0.76 | CCR5 (0.45) | RXRAPTGER1 | |
| SCHEMBL8161075 | 0.76 | LMNA (0.48) | PTGER1MEN1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | disclosed |