Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414452 | 0.88 | PTGIR (0.60) | PTGIRSIGMAR1PTGDRABCB1TBXAS1 | |
| SCHEMBL8811752 | 0.78 | SIGMAR1 (0.37) | SIGMAR1ABCB1PTGS2HTTMEN1 | |
| SCHEMBL8810160 | 0.75 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8830043 | 0.71 | SIGMAR1 (0.41) | PTGIRSIGMAR1PTGDRPTGS2ADORA3 | |
| SCHEMBL8811750 | 0.70 | ACHE (0.35) | PTGIRSIGMAR1 | |
| SCHEMBL8414449 | 0.69 | PTGIR (0.51) | PTGIRPTGDRTBXAS1ALDH1A1 | |
| SCHEMBL8808475 | 0.67 | PTGIR (0.47) | PTGIRSIGMAR1PTGDRABCB1ADORA3 | |
| SCHEMBL8414455 | 0.67 | CPB2 (0.35) | — | |
| SCHEMBL8809708 | 0.66 | PTGIR (0.39) | PTGIRSIGMAR1PTGDRABCB1MEN1 | |
| SCHEMBL8413331 | 0.66 | PTGIR (0.39) | PTGIRSIGMAR1PTGDRABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |