Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563886 | 0.85 | TP53 (0.41) | MAOBSMN1; SMN2 | |
| SCHEMBL11609893 | 0.77 | IDO1 (0.48) | MAOBSMN1; SMN2 | |
| SCHEMBL29255542 | 0.77 | MAOB (0.61) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL969878 | 0.76 | TSHR (0.46) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL11293541 | 0.76 | LMNA (0.67) | MAOBL3MBTL1GAAMAPTMAOA | |
| Butane SCHEMBL8010999 | 0.76 | PTGS1 (0.53) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL8814962 | 0.75 | ESR1 (0.40) | L3MBTL1LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL464352 | 0.75 | RXRA (0.66) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL19223062 | 0.75 | LTA4H (0.67) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL10051635 | 0.75 | TAAR1 (0.40) | MAPTSMN1; SMN2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011953-A1 | NOVEL HYDROXYLATED AND ALKOXYLATED N- AND/OR P-ARALKYLPHOSPHINIC ACID DERIVATIVES | NOVARTIS AG (CH) | 1997-04-03 | — | — | WO | disclosed |